New research details microplastics' impact on human cells critical to the male reproductive system. A study reveals they can impair the blood-testis barrier and damage Sertoli cells.
What's happening?
A study in the journal Ecotoxicology and Environmental Safety discovered microplastics have "underlying toxicity mechanisms." They could affect sperm production and development as well as human health.
Microplastics, plastic particles 5 millimeters or smaller, are everywhere: in oceans, in food, and in our blood.
This new study investigated the cytotoxicity of polystyrene microplastics (MPS). Exposure to it deformed 3D Sertoli cell spheroids (TM4S), models for the blood-testis barrier. Altered cells can lead to structural damage and toxic reproduction.
The study observed that smaller MPS particles (100 nm and 500 nm) could penetrate the spheroids. Larger particles (1 μm and 5 μm) clustered on the surface but could also invade at higher concentrations.
Regardless of size, MPS exposure triggered physiological stress in the cells. This included increased oxidative stress, inflammation, and apoptosis, or programmed cell death.
Find the best HVAC solution to heat and cool your home more efficiently Mitsubishi Electric’s efficient heating and cooling HVAC solutions can help you stay comfortable no matter the weather or region. You can even regulate temperatures in each room with individually controlled all-electric heat pump systems. With an energy-efficient, all-climate system from Mitsubishi, you can reduce the amount of energy needed to heat and cool your home, receive up to $2,000 in tax credits, and get peace of mind knowing you’re choosing rigorously tested, high-quality products. |
These findings suggest two things about TM4 cells. First, they keep the blood-testis barrier regulated; second, TM4 cells "[mediate] the reproductive toxicity of particulate matter."
Why are microplastics in the male reproductive system concerning?
The discovery raises significant concerns for human reproductive health.
Sertoli cells and the blood-testis barrier are crucial for maintaining male fertility. Damage to cells or the barrier can cause sperm abnormalities and reproductive toxicity.
Microplastics are already found in human blood, brains, placentas, and other organs. This study is another case of how plastic pollution might affect our bodies.
TCD Picks » Upway Spotlight
💡Upway makes it easy to find discounts of up to 60% on premium e-bike brands
|
How do you feel about microplastics being inside our bodies? Click your choice to see results and speak your mind. |
I want them out now 🚫 What's being done about microplastics in the body?
Further studies on MPS migration will continue to explore its behaviors and outcomes.
Research into the toxic effects of microplastics is vital to overcoming them. Insights like these will help develop protective strategies and inform regulatory safety assessments.
Reducing plastic production and consumption is the most direct way to limit microplastics. We can support policies that curb plastic waste and invest in recycling infrastructure.
We can use less plastic in our daily lives and choose sustainable alternatives. Reusable containers, bottles, and bags, and plastic-free packaging are viable options.
Scientific, proactive efforts against microplastics will lead toward a healthier, cleaner future.
Join our free newsletter for weekly updates on the latest innovations improving our lives and shaping our future, and don't miss this cool list of easy ways to help yourself while helping the planet.
Cool Picks
